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KMID : 0903519840270030151
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1984 Volume.27 No. 3 p.151 ~ p.157
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Biosynthesis of Skyrin in Penicillium islandicum
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Abstract
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Skyrin was extracted from Penicillium islandicum cultivated on synthetic Czapek-Dox medium. A preliminary experiment in Penicillium islandium using [^(14)C]-acetate proved the incorporation of [^(14)C] into skyrin. In the cell-free system using the fungus [³H]-emodin and [³H]-emodinanthrone were shown to give some reliable evidences far the biosynthesis of skyrin. The incorporation of [³H]-emodin was less significant than that of [³H]-emodinanthrone. As a result of the cell-free experiment, the biosynthetic pathway of skyrin by the fungus was suggested as follows: emodinanthrone→emodin→ skyrin.
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